Hiệu quả điều trị tăng sinh đơn giản điển hình nội mạc tử cung bằng Progestin
PGS. TS. Nguyễn Duy Tài
TÓM TẮT
Abstract
Endometrial hyperplasia is a common disease in pre- and perimenopausal women. The risk of progression of hyperplasia is endometrial cancer. Method: A clinical trial was carried out at Hungvuong hospital to evaluate the effectiveness of treatment of typical simple endometrial hyperplasia. 106 cases of typical simple endometrial hyperplasia at the hospital from May 2006 to June 2007,were conducted into the study. A 6-month course of Medroxyprogesteron acetat therapy was offered to all patients. The pathological response was evaluate from the histopathology of the endometrium after completion of the 6-month therapy.
Results: Clinical and pathological response rates are 92.45% and 91.5%. Significant factor predicting treatment non-responders is fibroma.
Conclusions: The current regimens of MPA therapy for typical simple endometrial hyperplasia have high response rates. Endometrial biopsy should be offered to the patients after treatment, because 8.5% have persistent lesions
Trích HN Việt - Pháp lần 8, năm 2008
